Archive | September 2018

October DNA Days (with me)

Blaine Bettinger, one of the best presenters and educators on genetic genealogy, is coming to Carlsbad, San Diego, for a daylong seminar next week on Saturday, October 6. This is a wonderful opportunity to gather knowledge from one of the stars of the field. At the moment, there are still a few seats open.

I will also be doing a workshop on working with your DNA matches that morning in Carlsbad. If you are interested in having your results be an example in my workshop, please contact me with some details.

The idea of a workshop is I talk briefly, then you try it yourselves. Then I talk some more. Then you try some more and we repeat again. So please bring your laptop or tablet or even make do with your smartphone and we will have fun! We will mainly work with Ancestry matches plus a little bit with GEDmatch. If you have not yet uploaded your DNA data to GEDmatch.com please do so. Click here for how.

Blaine’s workshop about visual phasing will be at the same time as mine. Everyone loves this workshop at Jamboree so it is great to have it locally. Blaine is not only the author of several books on genetic genealogy and a blog, but he also runs a FaceBook group of about 46K members called “Genetic Genealogy Tips & Techniques.” His latest endeavor is a web site for self paced learning called DNA Central.

If you cannot make it up to Carlsbad, then come hear me following Saturday Oct 13 when I will be talking to the San Diego Genealogy Society in the Lake Murray area.

Or if you are in New Mexico, I will be talking in Albuquerque New Mexico the following day, Sunday Oct 14!
Continue reading →

Going Gluten Free: What Does Your DNA Say?

Sep22

Celiac disease (CD) is an autoimmune system response to gluten which can damage the small intestine. Gluten is a protein found in wheat, barley, and rye. Added gluten is often used by commercial bakers to make breads rise faster.

So why are so many people claiming major benefits from going gluten free? I am usually dubious of the latest diet craze but …

I discovered that my usual morning congestion vanished after the first two weeks of a weight loss diet which had eliminated bread. It occurred to me that I had inadvertently been gluten free. So I asked a cousin who had given up gluten about her experience and she explained that her perpetual debilitating sinus infections were gone now. Still dubious, I added bread slowly back into my diet. One ear infection and much congestion later, I started to think that gluten might actually be a problem for me.

I wondered if there was anything reported on this in my DNA. I opened my latest 23andme Genetic Health Risk report (under the top menu item Health)

(red arrow added by me) and saw that I have an increased risk for celiac disease:

When I clicked the Slightly increased risk to get the report I saw this:

It is important to understand that having a genetic variant associated with a disease does not mean you will get it, just that you are more at risk. There are usually many other factors that are needed to cause the condition. Science is still at the very early stages of figuring out the roles our genes play in various diseases.

My initial research suggests that people with celiac disease (CD) just about always have one or both of these variants, however having them does not guarantee that you will have gluten issues.

Continue reading →

Finally, Ancestry’s New Ethnicity Estimates

Sep12

Today we all got an email from Ancestry announcing new ethnicity reports for everyone. Adding five times the reference populations plus a better algorithm that can often indicate the modern countries. This time I really do have the new ancestry composition estimates!

Naturally I immediately went and looked. Then I messaged and emailed all my tested cousins to accept the new update. When you log in to Ancestry and click on DNA in the top menu you get a page with three panels. Click on the panel to the left called “DNA story” to go to a page with a world map and the Updates Available box on the upper right.

Click the green button that says View your Updated Estimate in that box. Next you have to answer a few questions about your expectations and your thoughts on the previous ethnicity. I am afraid I did not understand that below each was a slider which I could move to indicate the level of accuracy, so until the last one that I answered, I left it alone. I wonder how many others will make that error.

The first time on your new ethnicity page, you will see a panel on the right showing how your estimates have changed. Here is mine. I was sad to say goodbye to that unlikely 1% Polynesian!

My father was Norwegian American with one fourth grandad (2% of his DNA?) who was German. My mother was born in Munich to a Jewish father and Bavarian Catholic mother. So how does that play out in these new estimates? Could the Swedish be a remnant from the 30 years war where Swedish soldiers rampaged through Bavaria? Actually I think my Norwegian dad had a fifth grandparent who was Swedish but that would hardly show either.

Here is my brother’s page showing the new estimates with the changes:

I am still 29% Jewish but my brother is down to 20% from 22%. Our maternal grandad was Jewish and I randomly got more of his DNA than my grandmother’s. When a 2nd cousin on our maternal grandmother’s side tested, my brother did indeed share a third again as much DNA with her as I did (Click here for that post)

By the way you can get back to the page showing the changes together with the new estimates by clicking on the small blue Updates at the top of your ethnicity estimate then the View Previous Estimate at the bottom of the Ethnicity box followed by Compare these results to your most recent AncestryDNA estimate on the next page.

Now to look at some more interesting ethnic makeups from my cousins and people I have helped.
Continue reading →

Ancestry’s Updated Ethnicity Reports

Sep1

UPDATE 3-SEP-2018: My apologies, my account and my cousins do NOT have the latest updates. Since they are more recent and prettier than the last time I looked, I had made that false assumption. Thanks to the members of the Ancestry DNA Matching Facebook group for showing me what the real update looks like.

To see what your version is click on the “up to date” or the “i” in a circle on top of your ethnicity results. Then it will show you a box that tells you what version you have. If you only have 3000 reference samples, then, like me, you do not have the very latest.

I look forward to writing a new post whenever I finally get those changed reports! Meanwhile this post may still be of some interest…

Original post was:

Over the summer Ancestry DNA has been rolling out their new ethnicity estimates and they have finally arrived in my account.

My brother’s ethnicity has not changed, it just has more features.

These changes have been made for two reasons. First of all, Ancestry has lots more data; they have added 13,000 new samples to an original group of 3,000 reference populations.* Secondly they have changed their algorithm to look at runs of DNA rather than just single points (23andme uses this technique as well). You can read their full explanation here: https://www.ancestry.co.uk/cs/dna-help/ethnicity/faq

The predictions for my brother, as shown above, have not changed (click here for my previous article on his ethnicity). He is still 62% Scandinavian (our Dad is Norwegian American) and 22% Jewish (Mom’s dad was German Jewish). While the Bavarian from Mom’s mother is still showing as Scandinavian, Europe South (this was Italy/Greece), and West European. The English comes from Dad according to various other sites where he was tested. This is discussed in my article Norwegian or English? where I suggest that it is the English who have some Norwegian.

The new presentation is prettier and it has some very accurate subcategories. Yes all our Norwegian ancestors are from the circled areas, Western and Southern Norway.

and my ancestors ended up in the city of Brooklyn, NY

One thing I find very enjoyable are the descriptions of the subgroups and migration groups. Also of interest is the story they tell you when you click on one of your groups and a date like 1875 as above.

My ancestry is different from my brother’s but not wildly so. I have more Jewish (German Jewish so within the predicted subgroup), less Scandinavian, and a few interesting bits of noise like Polynesian. I remember one ethnicity estimate somewhere which claimed I had 1% Amerind. I like to think there is a sprinkling of Sami that creates that blip.

I have examples from a wide variety of people thanks to the many adoptees and relatives that I have helped. By the way, my perfect cousin (who I often blog about) is still 100% Scandinavian with the expected subpopulations of South and East Norway.