Tag Archive | DNA health reports

Are you genetically resistant to AIDS?

There is a gene called CCR5 that can have a variation that prevents AIDS. You need to have two copies, one from each parent, to be immune to AIDS. If you have only one copy, your resistance is increased. The current theory is that this mutation became prevalent in Europeans after the ravages of smallpox or perhaps the Black Death and was selected for, since it is presumed protective against those diseases. It is more frequent in Northern Europe than Southern, but is found as far south as North Africa.

from wikipedia – By US National Institutes of Health – National Institute of Allergy and Infectious Diseases – US National Institutes of Health – National Institute of Allergy and Infectious Diseases, Public Domain, Link

The down side is that this CCR5 change may increase your risk of an abdominal aortic aneurysm and put you at risk for complications from various viruses like West Nile or tick born encephaliitis. Wikipedia has an excellent and detailed article about CCR5 here.

This AIDs protective variation is actually the loss of 32 alleles (so it is called delta 32) on chromosome 3 at location 46414947.

It is that change that the Genetics researcher He Jiankui claims to have made on two embryos in China using CRISPR technology which has caused such an uproar around the world. Click here for the NPR article about that which mentions that their father is HIV positive.

If you have tested your DNA at 23andme, you can check your own CCR5 for the delta 32 variation which is known as i3003626 there. Here’s how

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Big changes coming at 23andme, Health is back

23andMe Utube

Excerpt from the 23andme Reports Overview at Youtube

The price has gone up but so has the amount of information you will receive. Those of you who bought kits after the FDA shut down the health information at 23andme will now get the new improved reports. All of us testers will receive an email once our accounts have transitioned over.

I received 12 emails today announcing this! As soon as any of the accounts I manage transition over to the new software, I will write a report here on my blog. The accounts that already had health reports were promised in the email that they will “continue to have access to [their] current health reports. The new experience will include redesigned versions of many of the same health and ancestry reports that you currently have.”

Blogger Andrea Badger published the following report on the DNA-NEWBIE mailing list:

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