Archive by Author | Kitty

Eliminating the DNA Matches from One Side

UPDATE 26-Oct-2018: Click here for this tool  –  Extract Desired Lines

Unless you get lucky with a first cousin or closer match, searching for an unknown parent or grandparent involves building lots of trees for your DNA relatives and looking for common ancestors among them. Then you build down from those ancestors looking for someone in the right place at the right time. It is best to have two pairs of common ancestors because then you are looking for where their descendants meet in a marriage.

Sample ancestor list from GWorks – linked to slide in my GWorks presentation – using-dna-for-adoption-searches

It is wonderful to have automation to compare trees for you. The GWorks tool suite from DNAgedcom.com does just that and, no surprise, I have written many blog posts about how to use those tools. They can collect all your Ancestry matches and then all the ancestors in their DNA connected trees and give you a list of the most frequently seen ancestors. You can also upload GEDcoms collected elsewhere or created by your own research to use in the comparison.

There are many times I would like to automatically exclude half the ancestors collected from Ancestry. For example when I am helping a person who knows only one parent but has a half sibling or the known parent tested. Specifically when they look at the results from a GWorks run, how do they eliminate the matches from the other side?

View Trees with an example for deleting

One way is to go to the “View Trees” on the GWorks menu at DNAgedcom and delete all the trees from the known side by clicking the red X to the far right of each tree. Then rerun the “Match GEDcom files” in the Manage Tree Files function. This could take forever in a half sibling case.

However, it is very useful to delete trees when one person has tested multiple family members and they are all in the same tree. In that case I keep the tree for the person who is further up the line. Very conveniently you can click on the tree name to go to that match at Ancestry, as long as you are logged in there, so you can easily figure out which one to keep. But again, this is too lengthy a process for a half sibling case.

DNAgedcom client home window

I have long used the Match-O-Matic (M-O-M) feature in the DNAgedcom client (DGC) to get the lists of matches for just one side (the m_ file) in a spreadsheet for use to keep track of my research. However M-O-M does not work for the tree files (aka the a_ file – actually it has a list of ancestors and which trees they are from).

Sometimes it is good to be a programmer. I have put together a new tool that you can use with a list of matches, for example the match file from M-O-M, to create a new tree file with only those trees that are for the matches in the match file. Then you can upload that match file and the new tree file to DNAgedcom for use in GWorks.

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New Compact Chromosome Browser on GEDmatch’s GENESIS

Today GEDmatch launched a version of my segment mapper which is integrated with their database. It can be used as a way to easily visualize multiple matches on GENESIS. This first version shows how everyone compares to the first person on the list, like the current 2D chromosome browser but more compact. Also each color is a person.

My Munson cousins in my new compact segment mapper at Genesis

Above is the screenshot of my Munson cousins which even shows one of the boxes that appears when the cursor is placed on a segment. Click on this image to see a copy of the html version (edited for privacy) where you can put your cursor on any segment to see the details. (N.B. when you put your cursor on a segment and the information pops up via javascript that is called a mouse over in geek speak. )

One way to get a display like this at Genesis is to check the boxes (tier 1 only) next to your best matches in the one-to-many (up to 40 of them) and then click the button “Visualization” at the top of the page. Another way to get there is to use the Tier 1 tool “MultiKit Analysis” and select the kits you want to look at. Remember the first kit listed is the one that all the others will be compared to.

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When the DNA says your parents are related

One of the first things I do when helping someone with their DNA results is to check if their parents are related. This can explain unusual patterns of matches, for example, all seemingly from one side.

GEDmatch.com has a nice tool called “Are Your Parents Related” (AYPR) in the”Analyze Your Data” blue panel (middle right of page) which looks for places in the specified kit where the DNA is identical on both chromosome pairs, maternal and paternal. This happens when you inherit the same segment of DNA from each parent because they are related. We call this a homozygous run which is a fancy way of saying a stretch of identical DNA on both sides.

CeCe Moore specializes in helping people who make this discovery. Click here for the informational brochure she helped Brianne Kirkpatrick, genetic counselor, create. It includes where to get emotional support.

My goal is to help you figure out what the DNA means yourself. Can you deduce what the relationship of those parents is? Well a very simple rule of thumb is to multiply the shared DNA from AYPR tool by four and look up that new total at the DNA painter calculator for the possibilities. Then do further family DNA testing to confirm.

Why does this work? Let’s look at the numbers. Suppose your parents share 25% of their DNA. They will pass about half of that to you, so 12.5%. However only about half of that will be the same DNA so it will show up as about 6.25% on the AYPR tool.

Look at the image. The total is 215.3 when you multiply by 4 you get 861.2. You might look that up before you read on …

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My Recipes for Weight Control

Maintaining a sensible weight has always been a struggle for me so I object to 23andme saying “Kitty, your genes predispose you to weigh about 8% less than average.” I really want to blame my DNA for this excess weight, not the eating habits I learned growing up. My maternal grandparents were a bit pear-shaped when they were older. My mother and brother also always struggled with their weight … it has to be in my genes!

I have a simple five year plan for weight control: diet for six months to lose 15-20 pounds then eat for four plus years to gain 20-25. You can see how this long term trend is going! So this time I will try to lose 30 even if it takes over a year to do it.

Critical to my many previous successes has been a support person or group. Perhaps that is why I have done Weight Watchers so many times. The last two times my husband dieted with me and we did Nutrisystem quite successfully. This time I am doing South Beach with my friend Lynne (her choice) and I am quite pleased with it as I do not get very hungry nor crave .. chocolate … Low carb has always worked well for me. As a teenager all I had to do was give up dessert and hamburger buns for a week to lose 5 pounds.

Since a reader told me at a recent conference that she enjoyed my occasional off topic posts, I will share some of my low carb creations here. By the way, whenever I find a recipe online, somehow I always have to fiddle with it a little.

I prefer to start the day with a good breakfast so here is my own invention, an easy recipe for an open faced breakfast sandwich using a microwave and a toaster oven that works on Weight Watchers, Nutrisystem, (2 protein, 1 bread) and starting week 3 of South Beach. However my current weight loss stalled when I added back the whole wheat English muffin so I dropped that part of it and now serve mine on small slices of ham instead.
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An Online DNA Conference from FHF

The thing I have disliked in the past about doing webinars is the lack of audience feedback. I really enjoy explaining my passion to a group of people, seeing their reactions, and then answering their questions. That is so much better for me than talking into a microphone while going through my slides.

Practice FHF online presentation, Sam, Andy Noel of FHF, and myself (0nly one person shows when presenting)

The software that Family History Fanatics (FHF) uses for online conferencing lets me see the chat comments and shows my face in the corner while I present my slides. Plus I can switch to full face mode, which I plan to do when answering questions. I think this will be a much better way for me to do a webinar, so I welcome you all to register for the FHF one day DNA conference – A summer of DNA on Saturday, August 4. I will be joined by Diahan Southard, Sam Williams, and Michelle Leonard. After all the talks there will be a panel including a Q+A. Continue reading