Archive | July 2018

When the DNA says your parents are related

One of the first things I do when helping someone with their DNA results is to check if their parents are related. This can explain unusual patterns of matches, for example, all seemingly from one side.

GEDmatch.com has a nice tool called “Are Your Parents Related” (AYPR) in the”Analyze Your Data” blue panel (middle right of page) which looks for places in the specified kit where the DNA is identical on both chromosome pairs, maternal and paternal. This happens when you inherit the same segment of DNA from each parent because they are related. We call this a homozygous run which is a fancy way of saying a stretch of identical DNA on both sides.

CeCe Moore specializes in helping people who make this discovery. Click here for the informational brochure she helped Brianne Kirkpatrick, genetic counselor, create. It includes where to get emotional support.

My goal is to help you figure out what the DNA means yourself. Can you deduce what the relationship of those parents is? Well a very simple rule of thumb is to multiply the shared DNA from AYPR tool by four and look up that new total at the DNA painter calculator for the possibilities. Then do further family DNA testing to confirm.

Why does this work? Let’s look at the numbers. Suppose your parents share 25% of their DNA. They will pass about half of that to you, so 12.5%. However only about half of that will be the same DNA so it will show up as about 6.25% on the AYPR tool.

Look at the image. The total is 215.3 when you multiply by 4 you get 861.2. You might look that up before you read on …

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My Recipes for Weight Control

Maintaining a sensible weight has always been a struggle for me so I object to 23andme saying “Kitty, your genes predispose you to weigh about 8% less than average.” I really want to blame my DNA for this excess weight, not the eating habits I learned growing up. My maternal grandparents were a bit pear-shaped when they were older. My mother and brother also always struggled with their weight … it has to be in my genes!

I have a simple five year plan for weight control: diet for six months to lose 15-20 pounds then eat for four plus years to gain 20-25. You can see how this long term trend is going! So this time I will try to lose 30 even if it takes over a year to do it.

Critical to my many previous successes has been a support person or group. Perhaps that is why I have done Weight Watchers so many times. The last two times my husband dieted with me and we did Nutrisystem quite successfully. This time I am doing South Beach with my friend Lynne (her choice) and I am quite pleased with it as I do not get very hungry nor crave .. chocolate … Low carb has always worked well for me. As a teenager all I had to do was give up dessert and hamburger buns for a week to lose 5 pounds.

Since a reader told me at a recent conference that she enjoyed my occasional off topic posts, I will share some of my low carb creations here. By the way, whenever I find a recipe online, somehow I always have to fiddle with it a little.

I prefer to start the day with a good breakfast so here is my own invention, an easy recipe for an open faced breakfast sandwich using a microwave and a toaster oven that works on Weight Watchers, Nutrisystem, (2 protein, 1 bread) and starting week 3 of South Beach. However my current weight loss stalled when I added back the whole wheat English muffin so I dropped that part of it and now serve mine on small slices of ham instead.
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An Online DNA Conference from FHF

The thing I have disliked in the past about doing webinars is the lack of audience feedback. I really enjoy explaining my passion to a group of people, seeing their reactions, and then answering their questions. That is so much better for me than talking into a microphone while going through my slides.

Practice FHF online presentation, Sam, Andy Noel of FHF, and myself (0nly one person shows when presenting)

The software that Family History Fanatics (FHF) uses for online conferencing lets me see the chat comments and shows my face in the corner while I present my slides. Plus I can switch to full face mode, which I plan to do when answering questions. I think this will be a much better way for me to do a webinar, so I welcome you all to register for the FHF one day DNA conference – A summer of DNA on Saturday, August 4. I will be joined by Diahan Southard, Sam Williams, and Michelle Leonard. After all the talks there will be a panel including a Q+A. Continue reading