A team of Penn State researchers has made a map of human chromosomes that shows the areas where mutations are more and less frequent; in their words “mutationally hot and cold regions.” However I found their diagram extremely difficult to understand. It took me quite a while to figure out the areas that are hot and cold for the SNPs that genetic genealogists are interested in. So I redid their image, removing the color for microsatellite repeat alterations, and changed the colors a little to be more in tune with hot and cold for me.
Here is my version:
Gray presumably are the areas not done and white outlined with black shows the centromeres. The one place with the least mutation is the X chromosome.
No guarantees that my reinterpretation of the graph by Kateryna Makova and Francesca Chiaromonte is correct!
So what does this mean for genetic genealogists? Well I would think that matches in the pink or red areas (hottest and hot) are going to be more recent and perhaps findable. Personally that blue area of chromosome 9 is where my Dad and I match many many people with no possible ancestral connection to us in the last 500 or so years! None are from his ancestral home area (Southen Norway) and most of his lines are documented pretty far back.
Here is the full article:
Warning it uses highly technical terminology